Endothelin 1 (EDN1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC, R, WB
Recommend Dilution	RIA. EIA. Western blot. Immunohistochemistry on Paraffin Sections.
Reactivity	Bovine, Human, Porcine
Host	Rabbit
Clonality	Polyclonal
Immunogen	Human Endothelin-1
Specificity	This antibody detects Endothelin-1.
Formulation	State: Serum State: Lyophilized Serum without additives
Reconstitution Method	Restore in aqua bidest to initial volume.
Conjugation	Unconjugated
Storage Condition	Prior to reconstitution store at 2-8°C. Following reconstitution store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	endothelin 1
Database Link	Entrez Gene 1906 Human UniProt ID P05305
Background	Endothelins (ET) show potent constrictor activity in vascular and non-vascular smooth muscle. This family of 21-amino acid peptides exists in at least three isoforms - ET-1, ET-2, and ET-3, and is produced in endothelial and epithelial cells. ET's can mediate biological effects in cells and tissues, and have been shown to bind to an ET receptor in the lung, kidney, heart, and liver. Endothelin 1 is expressed in lung, placental stem villi vessels and in cultured placental vascular smooth muscle cells.
Synonyms	PPET1, EDN1, ET1, HDLCQ7, EDN1
Reference Data

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