Natriuretic Peptide Receptor C (NPR3) (199-213) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	Western blot (1/1000). Immunocytochemistry: 1/800. Immunofluorescence on Cryosections: 1/800.
Reactivity	Human, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic Human NPR-C (199-213) poly Lysin conjugated
Specificity	This antibody detects synthetic Human NPR-C (aa 199-213), Rat NPR-C.
Formulation	State: Serum State: Lyophilized Serum
Reconstitution Method	Restore in aqua bidest to initial volume.
Conjugation	Unconjugated
Storage Condition	Store lyophilized at 2-8°C and reconstituted at -20°C. Avoid repeated freezing and thawing.
Gene Name	natriuretic peptide receptor 3
Database Link	Entrez Gene 4883 Human UniProt ID P17342
Background	The family of natriuretic peptides elicits a number of vascular, renal and endocrine effects that are important in the maintenance of blood pressure and extracellular fluid volume. These effects are mediated by specific binding of the peptides to cell surface receptors in the vasculature, kidney, adrenal and brain. Natriuretic peptide receptor C does not exhibit guanylate cyclase activity. There seem to be at least three ANP receptors: two with guanylate cyclase activity (ANPA and ANPB) and one (ANPC) which is probably responsible for the clearance of ANP from the circulation without a role in signal transduction.
Synonyms	Atrial natriuretic peptide C-type receptor, ANP clearance receptor, ANP-C, NPR-C
Note	LocusID 4883
Reference Data

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