BCL2 Sheep Polyclonal Antibody

Specifications

Product Data
Applications	IF, IP, WB
Recommend Dilution	Western Blot: 1:5,000. Immunoprecipitation. Immunofluorescence: 1:5000.
Reactivity	Canine, Human, Rat
Host	Sheep
Clonality	Polyclonal
Immunogen	Full length recombinant bcl-2 protein
Specificity	This antibody reacts to bcl-2.
Formulation	Phosphate buffered saline with 0.08% sodium azide State: Purified State: Liquid purified Ig (0.2µm sterile filtered)
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store the antibody at -20°C. Avoid repeated freezing and thawing.
Gene Name	B-cell CLL/lymphoma 2
Database Link	Entrez Gene 596 Human UniProt ID P10415
Background	Human hematopoetic malignancies are often characterized by gene rearrangements that deregulate gene expression. Antibodies to human bcl-2 (B cell leukemia/lymphoma 2) are directed against the gene isolated at the chromosomal breakpoint t(14;18) Bcl-2 which suppress programmed cell death (apoptosis) and appears to be modulated by association with bax, a cell death promoter.
Synonyms	BCL2, Bcl-2 alpha
Reference Data

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