ACVR1 Sheep Polyclonal Antibody

CAT#: AP05119PU-N

ACVR1 sheep polyclonal antibody, Purified



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CNY 7,240.00


货期*
4周

规格
    • 250 ug

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Specifications

Product Data
Applications IHC, IP, WB
Recommend Dilution Western Blot: 5 - 10 µg/ml.
Immunoprecipitation: 5 µg/mg of protein lysate.
Immunohistochemistry on paraffin sections: 5 - 10 µg/ml.
Reactivity Chicken
Host Sheep
Clonality Polyclonal
Immunogen Recombinant protein derived from the extracellular domain of the chicken ALK2 protein. Protein shares significant homology with the mouse, rat and human sequences.
Specificity This antibody reacts to ALK2.
Formulation Phosphate buffered saline with 0.08% sodium azide
State: Purified
State: Liquid purified Ig
Concentration lot specific
Conjugation Unconjugated
Storage Condition The antibody can be shipped at ambient temperature. Store (in aliquots) at -20°C only.
Avoid repeated freezing and thawing.
Gene Name activin A receptor, type I
Background Activin Receptor-Like Kinase 2 is a member of the superfamily of type I receptors for transforming growth factor-beta (TGF-beta). This receptor binds both activin and bone morphogenic proteins (BMPs). In mice, these receptors are expressed mainly in the extraembryonic visceral endoderm before gastrulation and later in both embryonic and extraembryonic cells during gastrulation. Also, it has been shown that ALK2 associates with and phosphorylates Smad1 and also regulated Smad5 and Smad8 phosphorylation. It also induces the Tlx2 promoter in the absense of BMP7.
Synonyms Activin receptor type IA, ACVRLK2, ALK2, SKR1, ACRV1A
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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