CACNB3 Rabbit Polyclonal Antibody
CAT#: AP05139PU-N
CACNB3 rabbit polyclonal antibody, Purified
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CNY 5,937.00
货期*
4周
规格
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Specifications
Product Data | |
Applications | WB |
Recommend Dilution | Western Blot: 5 - 10 µg/ml. |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide derived from the rat beta3 calcium channel conjugated to KLH. |
Specificity | This antibody reacts to CACNB3. |
Formulation | Phosphate buffered saline with 0.08% sodium azide State: Purified State: Liquid purified Ig |
Concentration | lot specific |
Conjugation | Unconjugated |
Storage Condition | The antibody can be shipped at ambient temperature. Store (in aliquots) at -20°C only. Avoid repeated freezing and thawing. |
Gene Name | calcium voltage-gated channel auxiliary subunit beta 3 |
Database Link | |
Background | Voltage-sensitive calcium channels (VSCCs) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, benzothiazepines, and by omega-agatoxin-IIIA (omega-aga-IIIA). They are however insensitive to omega-conotoxin-GVIA (omega-ctx-GVIA) and omega-agatoxin-IVA (omega-aga-IVA). The overall conclusion is that deletion of the beta 3 subunit affects at least three distinct types of High voltage activated Ca2+ channel (L,N and P/Q types), but no single type of channel is solely dependent on beta 3. |
Synonyms | CAB3, CACNLB3 |
Reference Data |
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