G protein alpha inhibitor 1 (GNAI1) (+ GNAI2) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	Western Blot: 5 - 10 µg/ml.
Reactivity	Bovine, Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Peptide corresponding to amino acids 345 - 354 of Gialpha1 and 346-355 of Gialpha2.
Specificity	This antibody reacts to Gi alpha 1/2.
Formulation	Phosphate buffered saline with 0.08% sodium azide State: Purified State: Liquid purified Ig
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	The antibody can be shipped at ambient temperature. Store (in aliquots) at -20°C only. Avoid repeated freezing and thawing.
Gene Name	G protein subunit alpha i1
Database Link	Entrez Gene 14677 MouseEntrez Gene 25686 RatEntrez Gene 2770 Human UniProt ID P63096
Background	GTP-binding proteins (G-proteins) play a critical role in signal transduction by coupling receptors to effectors. The intracellular consequences of G-protein activation include second messenger generation, protein phosphorylation, ion channel activation, gene induction, cell growth, and differentiation. Gi belongs to the pertussis toxin sensitive G-proteins. Gi consists of three different subtypes of alpha-subunits (alphai1, aalphai2 and alphai3)
Synonyms	GNAI1
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Axon guidance, Chemokine signaling pathway, Gap junction, Leukocyte transendothelial migration, Long-term depression, Melanogenesis, Progesterone-mediated oocyte maturation, Tight junction

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