UGT8 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, WB
Recommend Dilution	ELISA. Western Blot: 5-10 µg/ml. Positive Control: Found in all tissues examined.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide derived from Human Ceramide Glycosyltransferase Protein
Specificity	This antibody recognizes Human Ceramide Glycosyltransferase. Other species not tested.
Formulation	PBS State: Purified State: Liquid purified Ig fraction Preservative: 0.08% Sodium Azide
Concentration	lot specific
Purification	Ammonium Sulfate Precipitation
Conjugation	Unconjugated
Storage Condition	Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing.
Gene Name	UDP glycosyltransferase 8
Database Link	Entrez Gene 7368 Human UniProt ID Q16880
Background	May serve as a flippase as well as a glucosyltransferase that transfers glucose to ceramide. It Catalzes; UDP-glucose + Nacylsphingosine = UDP + D-glucosyl-N-acylsphingosine. Ceramide Glycosyltransferase is the first step in the Glycosphingolipid synthesis; first glycosylation step. Glucosylceramide synthase (GlcT) and lactosylceramide synthase (GalT) are key enzymes for the synthesis of major glycosphingolipids of vertebrates.
Synonyms	UDP-galactose-ceramide galactosyltransferase, Ceramide UDP-galactosyltransferase, Cerebroside synthase, CGT
Reference Data
Protein Families	Transmembrane
Protein Pathways	Metabolic pathways, Sphingolipid metabolism

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