SPTLC1 Rabbit Polyclonal Antibody
CAT#: AP05262PU-N
SPTLC1 rabbit polyclonal antibody, Purified
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CNY 5,937.00
货期*
4周
规格
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Specifications
Product Data | |
Applications | WB |
Recommend Dilution | Western Blot (1-5 µg/ml). |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide derived from the human serine palmitoyltransferase enzyme |
Specificity | This antibody detects Serine Palmitoyltransferase 1. |
Formulation | Phosphate buffered saline with 0.08 % sodium azide State: Purified State: Liquid purified Ig fraction |
Concentration | lot specific |
Conjugation | Unconjugated |
Storage Condition | Store the product (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C. Avoid repeated freezing and thawing. |
Gene Name | serine palmitoyltransferase long chain base subunit 1 |
Database Link | |
Background | Sphingolipids play essential roles in various cellular events, including proliferation, differentiation, senescence, apoptosis, and inflammatory responses. Serine palmitoyltransferase (SPT) is the initial and rate-limiting enzyme in the de novo sphingolipid biosynthesis, and thus regulates the level of sphingolipids in cells. Immunohistochemical study revealed widespread distribution of the enzyme with most strong expression in brain and digestive tract. Two subunits, SPT1 and SPT2 at a stoichiometry of 1:1, are involved in the enzymatic activity of SPT. |
Synonyms | Serine palmitoyltransferase 1, SPT 1, SPT1, LCB 1, LCB1 |
Reference Data | |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Metabolic pathways, Sphingolipid metabolism |
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