Corticosterone Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA
Recommend Dilution	ELISA: 1/500 -1/10.000
Reactivity	Broad
Host	Rabbit
Clonality	Polyclonal
Immunogen	Corticosterone 3 -BSA conjugate
Specificity	This antibody is specific for Corticosterone, a steroid hormone which is produced by the adrenal gland. It is the major glucocorticoid in many species, having a role in stress response and immune reactions. This antibody show minimal cross-reactivity with the following related hormones: 11-Deoxycorticosterone: 1% Cortisol: 0.1% Progesterone: 0.02% Testosterone: < 0.01%
Formulation	PBS, pH 7.2 State: Purified State: Liquid purified IgG fraction Preservative: 0.09% Sodium Azide
Concentration	lot specific
Purification	Affinity Chromatography on Protein G
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Background	Corticosterone is a steroid hormone secreted by the outer layer, or cortex, of the adrenal gland . Classed as a glucocorticoid, corticosterone helps regulate the conversion of amino acids into carbohydrates and glycogen by the liver, and helps stimulate glycogen formation in the tissues. Corticosterone is similar in structure, although somewhat less potent, than the other glucocorticoids cortisol and cortisone . It is produced in response to stimulation by the pituitary substance adrenocorticotropic hormone (ACTH). In some species, but not in humans, corticosterone is the predominant glucocorticoid secreted by the adrenal. It is a precursor in the synthesis of aldosterone , another adrenal cortical steroid.
Reference Data

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