Col1a1 Rabbit Polyclonal Antibody
CAT#: AP05388PU-N
Col1a1 rabbit polyclonal antibody, Purified
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CNY 6,919.00
货期*
4周
规格
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Specifications
Product Data | |
Applications | ELISA, IF, IHC, R |
Recommend Dilution | ELISA: 1/100-1/400. Immunofluorescence: 1/50-1/100. Radioimmunoassays. Immunohistochemistry on Frozen Sections. Immunohistochemistry on Paraffin Sections: 1/250-1/1000. |
Reactivity | Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Native type I Collagen from Mouse skin. |
Specificity | This antibody is specific for Mouse Collagen type I. Less than 1% cross reactivity has been observed with Mouse Collagen, types II, VI and III and Human, Chicken and Rat Collagen, type I. |
Formulation | Phosphate buffered saline containing 0.09% Sodium Azide as preservative. State: Purified State: Liquid purified Ig fraction |
Purification | Affinity Chromatography |
Conjugation | Unconjugated |
Storage Condition | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Gene Name | collagen, type I, alpha 1 |
Database Link | |
Background | Collagens are highly conserved throughout evolution and are characterised by an uninterrupted "Glycine X Y" triplet repeat that is a necessary part of the triple helical structure. Type I collagen (95 kDa) is found in bone, cornea, skin and tendon. Mutations in the encoding gene are associated with osteogenesis imperfecta, Ehlers Danlos syndrome, and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for Platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. |
Synonyms | COL1A1, COL1A2, Alpha-1 type I collagen, Alpha-2 type I collagen |
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