IRF7 (C-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	Western blot: 1.0-2.0 µg/ml. This antibody detects a band of approximately 51kDa in 293 whole cell lysate.
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	14 amino acid peptide sequence near the carboxy terminus of Human IRF7.
Specificity	This antibody detects an epitope within the C-terminal of Human Interferon Regulatory Factor 7 (IRF7).
Formulation	PBS containing 0.02% Sodium Azide as preservative. State: Purified State: Liquid purified IgG fraction.
Concentration	lot specific
Purification	Affinity Chromatography.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	interferon regulatory factor 7
Database Link	Entrez Gene 3665 Human UniProt ID Q92985
Background	IRF7 is a 54kD transcriptional activator of type I interferons (IFNalpha/beta) in response to local and systemic viral infection. IRF7 is mostly expressed by plasmacytoid dendritic cells (pDC), which differentiate in response to IFNs and virus infection. This then stabilizes the IRF7 protein, in turn leading to increased IFN production. Multiple IRF7 transcript variants have been identified, although their individual functions have not yet been established.
Synonyms	IRF-7
Reference Data

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