Cardiac Troponin I (TNNI3) Goat Polyclonal Antibody

CAT#: AP05656PU-N

Cardiac Troponin I (TNNI3) goat polyclonal antibody, Purified



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CNY 5,555.00


货期*
4周

规格
    • 200 ug

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Specifications

Product Data
Applications ELISA
Recommend Dilution ELISA.
Reactivity Human
Host Goat
Clonality Polyclonal
Immunogen Native human cardiac troponin I, purity greater than 98%.
Specificity This antibody recognises human cardiac-specific troponin I, (TnI) an integral inhibitory protein of cardiac muscle which exists as a complex with troponin C (TnC) and troponin T (TnT).
Formulation PBS buffer pH 7.4 containing 0.09% Sodium Azide (NaN3)
State: Purified
State: Liquid purified IgG
Concentration lot specific
Purification Immunoaffinity chromatography
Conjugation Unconjugated
Storage Condition Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Gene Name troponin I3, cardiac type
Background The TnT subunit of troponin binds to tropomyosin to form a troponin-tropomyosin complex, anchored in place by the binding of TnI to actin, within muscle thin filaments. Structural change resulting from the binding of calcium to specific sites on the regulatory TnC subunit, releases the inhibitory region of TnI from actin, enabling the attachment of the molecular motor protein myosin, allowing for muscle contraction and hence movement. The measurement of blood TnI and TnT levels is an important diagnostic indicator of heart muscle damage, and can be used to differentiate between angina and myocardic infarction in patients with chest pain. Troponin I has also been shown to inhibit angiogenesis in vivo and in vitro.
Synonyms TNNI3, TNNC1
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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