Ppard (N-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, WB
Recommend Dilution	ELISA: 1:2000 - 1:8000. Western Blot: 1:500 - 1:2000; detects a band of approximately 55kDa in heart whole cell lysates.
Reactivity	Human, Monkey, Mouse, Rabbit, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Syntetic peptide corresponding to amino acids 1-14 of mouse PPAR delta.
Specificity	This antibody detects peroxisome proliferator-activated receptor, delta (PPARD).
Formulation	Phosphate buffered saline pH7.2 containing 0.01% Sodium Azide (NaN3) State: Purified State: Liquid purified IgG
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	peroxisome proliferator activator receptor delta
Database Link	Entrez Gene 5467 HumanEntrez Gene 25682 RatEntrez Gene 19015 Mouse UniProt ID P35396
Background	PPARD is a member of the nuclear hormone receptor subfamily. Upon activation, PPARD forms heterodimers with retinoid X receptors (RXRs), and functions to regulate transcription of specific gene sequences. PPARD controls genes involved in lipid metabolism, and enhances fatty acid catabolism and energy uncoupling in adipose tissue and skeletal muscle. PPARD has also been implicated in the proliferation and differentiation of preadipocytes, enterocytes, keratinocytes and the placenta. PPARD agonists could be used therapeutically to target multiple components of the metabolic syndrome, including insulin resistance, hyperglycemia, dyslipidemia, and atherosclerosis.
Synonyms	PPAR-beta, Nuclear hormone receptor 1, NUCI, PPARD, NR1C2, PPARB
Reference Data

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