CX3CR1 (N-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	Western Blot: 0.5-1.0 µg/ml. Detects a band of approximately 50kDa in Human spleen cell lysates. Immunohistochemistry on Paraffin Sections: 2.0 µg/ml. Requires Antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 is recommended for this purpose. Positive Control: Human Heart Tissue.
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	A peptide corresponding to amino acids 2-21 of Human CX3CR1.
Specificity	This antibody recognizes an epiptope within the N-terminal region (NT) of Human CX3CR1, a 40.4kDa seven trans-membrane protein.
Formulation	PBS State: Purified State: Liquid purified IgG fraction Preservative: 0.02% Sodium Azide
Concentration	lot specific
Purification	Affinity Chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	C-X3-C motif chemokine receptor 1
Database Link	Entrez Gene 13051 MouseEntrez Gene 171056 RatEntrez Gene 1524 Human UniProt ID P49238
Background	CX3CR1, known also as fractalkine receptor, is the receptor for CX3CL1 and acts as a co-receptor with CD4 for the HIV-1 envelope protein. It is expressed in a variety of human tissues and mediates leucocyte adhesion and migration.
Synonyms	CX3C chemokine receptor 1, C-X3-C CKR-1,CMKBRL1, CMK-BRL-1
Reference Data
Protein Families	Druggable Genome, GPCR, Transmembrane
Protein Pathways	Chemokine signaling pathway, Cytokine-cytokine receptor interaction

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