BAI1 (ADGRB1) (N-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC
Recommend Dilution	ELISA. Immunohistochemistry on Paraffin Sections: 10 - 15 µg/ml.
Reactivity	Human, Mouse, Bovine, Monkey
Host	Rabbit
Clonality	Polyclonal
Immunogen	BAI1 antibody was raised against synthetic 18 amino acid peptide from N-terminus of human BAI1.
Specificity	This antibody detects Brain-Specific Angiogenesis Inhibitor 1 (BAI1) at N-terminal domain.
Formulation	PBS containing 0.09% sodium azide as preservative State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Immunoaffinity chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C to -70°C for longer. Avoid repeated freezing and thawing.
Gene Name	adhesion G protein-coupled receptor B1
Database Link	Entrez Gene 575 Human UniProt ID O14514
Background	BAI1 is an Orphan-B GPCR with an unknown ligand. BAI1 is postulated to be a member of the secretin receptor family, an inhibitor of angiogenesis, and a growth suppressor of glioblastoma. Along with BAI1, there are two other brain-specific angiogenesis inhibitor genes, designated BAI2 and BAI3, which have similar tissue specificities and structures. However, only BAI1 is transcriptionally regulated by p53. Loss of BAI1 expression has been implicated in glioblastoma.
Synonyms	BAI-1
Reference Data

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