IEX1 (IER3) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	Immunohistochemistry on Paraffin Sections: 5 µg/ml. Western Blot: 2 - 4 µg/ml.
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide - KLH conjugated corresponding to a 24 amino acid peptide near the center of Human IEX1
Specificity	A 24 amino acid peptide near the center of Human IEX1.
Formulation	PBS containing 0.02% Sodium Azide as preservative State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Immunoaffinity Chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C. DO NOT FREEZE!
Gene Name	immediate early response 3
Database Link	Entrez Gene 8870 Human UniProt ID P46695
Background	IEX-1 was originally characterized as a gene induced by ultraviolet radiation and TNF-alpha, which protected human squamous carcinoma cells from apoptosis. Subsequent transfection studies have also shown that expression of IEX-1 in human keratinocytes and mouse fibroblasts results in more rapid proliferation of the cells as compared with controls. The IEX-1 promoter contains binding motifs for both NFKB and p53, suggesting that these proteins may regulate its expression. IEX-1 expression may be modulated by AML1 and TPO.
Synonyms	DIF2, IEX-1, PRG1, GLY96
Reference Data

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