TRPC6 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	Western Blot: 1/500-1/1000.
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Peptide Corresponding to the amino terminal sequence derived from Mouse TRPC6.
Specificity	Recognizes TRPC6.
Formulation	Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl State: Aff - Purified State: Liquid purified IgG fraction Stabilizer: 50% Glycerol Preservative: 0.02% Sodium Azide
Concentration	lot specific
Purification	Affinity Chromatography using epitope-specific immunogen
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	transient receptor potential cation channel subfamily C member 6
Database Link	Entrez Gene 7225 Human UniProt ID Q9Y210
Background	The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2).
Synonyms	Transient receptor protein 6, TRP-6
Reference Data

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