GFAP Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC
Recommend Dilution	Immunohistochemistry. Immunocytochemistry. Suitable for Frozen or Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections and cell smears: 1/50-1/200 using streptavidin~biotin system or polymer system. Recommended Positive Control:Human brain or astrocytoma.
Reactivity	Bovine, Guinea Pig, Human, Mouse, Porcine, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Purified Human GFAP.
Specificity	This antibody stains astrocytes, glial cells, ependymal cells and their corresponding tumors. In the peripheral nervous system , it stains Schwann cells, satellite and enteric glial cells. This antibody distinguishes neoplasm of astrocytes origin from other neoplasm of CNS. Cellular Localization: Cytoplasmic.
Formulation	PBS, pH 7.4 State: Purified State: Liquid purified Ig fraction Stabilizer: 1% BSA Preservative: 0.05% Sodium Azide
Concentration	lot specific
Purification	Protein A Chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	51 kDa (Antigen)
Gene Name	glial fibrillary acidic protein
Database Link	Entrez Gene 14580 MouseEntrez Gene 24387 RatEntrez Gene 2670 Human UniProt ID P14136
Background	Gilial Fibrillary acidic protein (GFAP), a 51 kDa an intermediate filament protein is closely related to non-epithelial family members, Vimentin, desmin and peripherin, which are all involved in structure and function of cell cytoskeleton. GFAP is expressed in central nervous system (CNS) in the astrocytes cells, functioning in cellular processes e.g. cell structure, movements, cell communication, brain processes and brain functions.
Synonyms	Glial Fibrillary Acidic Protein
Reference Data
Protein Families	ES Cell Differentiation/IPS

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