SLC40A1 (N-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC, WB
Recommend Dilution	ELISA: 1 µg/ml. Immunohistochemistry on Paraffin Sections: 20 µg/ml. Western Blot: 1 µg/ml.
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide - KLH conjugated corresponding to N-terminal residues of Human MTP1 (Metal Transporter Protein 1).
Specificity	This antibody recognizes MTP1/SLC40A1 (N-term).
Formulation	PBS containing 0.01% Sodium Azide as preservative and 50% Glycerol as stabilizer. State: Aff - Purified State: Liquid purified Ig fraction.
Concentration	lot specific
Purification	Immunoaffinity Chromatography.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	solute carrier family 40 member 1
Database Link	Entrez Gene 30061 Human UniProt ID Q9NP59
Background	SLC40A1 may be involved in iron export from duodenal epithelial cells and also in transfer of iron between maternal and fetal circulation. It mediates iron efflux in the presence of a ferroxidase (hephaestin and/or ceruloplasmin). Defects in SLC40A1 are the cause of hemochromatosis type 4, an autosomal dominant iron-loading disorder characterized by early iron accumulation in reticuloendothelial cells and a marked increase in serum ferritin.
Synonyms	Slc40a1, Fpn1, Ireg1, Slc11a3, Slc39a1, Ferroportin-1, Iron-regulated transporter 1, Metal transporter protein 1
Note	Predicted Molecular Weight: 63 kDa
Reference Data

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