TRIM25 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IF, IHC, WB
Recommend Dilution	ELISA. Immunocytochemistry: 20 µg/ml. Immunohistochemistry on Paraffin Sections: 10 µg/ml. Western Blot: 1 - 2 µg/ml.
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide
Specificity	This antibody reacts to Zinc Finger Protein 147.
Formulation	PBS containing 0.02% sodium azide State: Aff - Purified State: Liquid purified Ig
Concentration	lot specific
Purification	Immunoaffinity Chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	tripartite motif containing 25
Database Link	Entrez Gene 7706 Human UniProt ID Q14258
Background	The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc binding domains, a RING, a B box type 1 and a B box type 2, and a coiled coil region. The protein localizes to the cytoplasm. The presence of potential DNA binding and dimerization transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene.
Synonyms	ZNF147, EFP, RING finger protein 147
Reference Data

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