CCL3L3 Rabbit Polyclonal Antibody

CAT#: AP09165PU-S

CCL3L3 rabbit polyclonal antibody, Aff - Purified

Size: 100 ug 25 ul



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CNY 2,717.00


货期*
4周

规格
    • 25 ul

Product images

Specifications

Product Data
Applications ELISA, WB
Recommend Dilution Western Blot: 1,0 µg/ml.
ELISA.
Reactivity Porcine
Host Rabbit
Clonality Polyclonal
Immunogen Recombinant protein raised in yeast, corresponding to the 70 amino acids of the mature swine CCL3L1 protein.
Specificity This antibody reacts to CCL3L1.
Formulation 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01% (w/v) Sodium Azide
State: Aff - Purified
State: Lyophilized
Reconstitution Method Restore with 0.1 mL of deionized water (or equivalent).
Concentration lot specific
Purification Affinity chromatography on Protein A
Conjugation Unconjugated
Storage Condition Prior to reconstitution store at 2-8°C.
Following reconstitution store the antibody undiluted at 2-8°C for one month
or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Gene Name C-C motif chemokine ligand 3 like 3
Background Chemokine (C-C motif) ligand 3-like 1 (CCL3L1), also known as macrophage inflammatory protein 1 alpha (MIP-1 alpha; other synonyms: ld78beta, scya3l1, small inducible cytokine a3-like 1), is a member of the CC or beta chemokine subfamily that was originally purified from the conditioned media of an LPS-stimulated murine macrophage cell line. In humans, CCL3L1 is encoded by a variable copy-number gene. The CC family induces MCP1 and RANTES, and exhibits a variety of proinflammatory activities including chemotaxis, and functional and proliferative activation of leukocytes, lymphocytes, and macrophages. Its signal is transmitted through transmembrane receptors, CC chemokine receptors, CCR1, CCR3 and CCR5. CCL3L1/MIP-1 alpha acts as a chemoattractant to a variety of cells including monocytes, T cells, B cells and eosinophils. CCL3L1 binds to several chemokine receptors. In humans these receptors include chemokine binding protein 2 and chemokine (C-C motif) receptor 5 (CCR5). CCR5 is a co-receptor for HIV, and binding of this protein to CCR5 inhibits HIV entry. In swine, CCL3L1 protein is 86% similar to CCL4 protein, and 73% similar to CCL5.
Synonyms C-C motif chemokine 3-like 1, Small-inducible cytokine A3-like 1, D17S1718, G0S19-2, SCYA3L1
Reference Data
Protein Families Druggable Genome
Protein Pathways Chemokine signaling pathway, Cytokine-cytokine receptor interaction
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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