CHK1 (312-327) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, WB
Recommend Dilution	ELISA: 1/2,000 - 1/10,000. Western Blot: 1/200 - 1/2,000.
Reactivity	Yeast
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding aa 312-327 of S. cerevisiae CHK1
Specificity	This antibody is directed against yeast CHK1 protein.
Formulation	0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01% (w/v) Sodium Azide State: Aff - Purified State: Liquid purified Ig
Concentration	lot specific
Purification	Affinity chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody at -20°C. Avoid repeated freezing and thawing.
Database Link	UniProt ID P38147
Background	CHK1 (also known as serine/threonine-protein kinase CHK1 and checkpoint kinase 1) is involved in cell cycle arrest when DNA damage has occurred or when unligated DNA is present. The kinase controls phosphorylation and abundance of PDS1 to prevent anaphase entry. Also helps prevent mitotic exit. CHK1 is localized within the nucleus.
Synonyms	CHEK1, CHEK-1
Reference Data

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