c Rel (REL) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF
Recommend Dilution	Immunofluorescence: 1/100 - 1/200.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthesized non-phosphopeptide derived from human Rel around the phosphorylation site of serine 503 (T-S-SP-D-S)
Specificity	Rel Antibody detects endogenous levels of total Rel protein.
Formulation	Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol State: Aff - Purified State: Liquid purified Ig
Concentration	lot specific
Purification	Affinity chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody at -20°C. Avoid repeated freezing and thawing.
Gene Name	REL proto-oncogene, NF-kB subunit
Database Link	Entrez Gene 5966 Human UniProt ID Q04864
Background	c-Rel is the cellular cognate of v-Rel, the avian reticuloendo-theliosis virus strain T transforming gene. V-Rel encodes a 59kDa phosphoprotein that is located in the cytoplasm of transformed spleen cells and in the nucleus of non-transformed fibroblasts, in contrast to the c-Rel protein which is cytoplasmic. C-Rel was shown to represent a constituent of the kB site binding transcription factor NFkB, which plays a crucial role in the expression of immunoglobulin k light chain gene.
Synonyms	c-Rel
Reference Data
Protein Families	Druggable Genome, Transcription Factors

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