Cytokeratin 3 (KRT3) Guinea Pig Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC
Recommend Dilution	Immunofluorescence. Immunohistchemistry on Frozen Sections: 1/100-1/200.  Incubation Time: 1h at RT. Positive Control: Human cornea.
Reactivity	Human, Mouse
Host	Guinea Pig
Clonality	Polyclonal
Immunogen	Synthetic peptide of Human keratin K3 (formerly also designated cytokeratin 3; C- IKF SQS SQS SQR YSR), coupled to KLH
Specificity	MW 63,000 (pI 7.5) intermediate filament polypeptide, keratin K3, detected by Immunohistochemistry in the cornea only. Useful as a marker for corneal type differentiation (positive for epithelial cells of cornea) and for studying corneal epithelial stem cells.
Formulation	State: Serum State: Liquid Serum Preservative: 0.09% Sodium Azide, 0.5% BSA
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C.
Gene Name	keratin 3
Database Link	Entrez Gene 3850 Human UniProt ID P12035
Background	Cytokeratin 3 belongs to the intermediate filament family. It is a type II cytokeratin and is specifically expressed in the corneal epithelium. Cytokeratin 3 associates with Cytokeratin 12. Defects in Cytokeratin 3 are a cause of Meesmann corneal dystrophy.
Synonyms	Keartin-3, KRT3, Type-II keratin Kb3
Reference Data

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