5HT6 Receptor (HTR6) (C-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	Immunohistochemistry on Paraffin Sections: 2.5 - 5 µg/ml.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	HTR6 / 5-HT6 Receptor antibody was raised against synthetic 17 amino acid peptide from C-terminus of human HTR6 / 5-HT6. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla (100%); Monkey, Horse (94%); Gibbon, Dog, Rabbit (88%); Elephant (82%).
Specificity	The antibody recognizes the human Serotonin (5-hydroxytryptamine) receptor 6. Other species not tested. Epitope: C-terminal domain of human.
Formulation	PBS, pH 7.7, containing 0.09% sodium azide State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Peptide immunogen affinity chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	5-hydroxytryptamine receptor 6
Database Link	Entrez Gene 3362 Human UniProt ID P50406
Background	5-HT6 (HTR6) is a receptor for 5-hydroxytryptamine (Serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. 5-HT6 has been reported primarily in striatum of the brain. Expression has also been seen in stomach, spinal cord, and the lymphoid tissues of rats, including peripheral blood lymphocytes, spleen, and thymus.
Synonyms	5-hydroxytryptamine receptor 6, 5-HT-6
Reference Data
Protein Families	Druggable Genome, GPCR, Transmembrane
Protein Pathways	Calcium signaling pathway, Neuroactive ligand-receptor interaction

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