Transglutaminase 2 (TGM2) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, WB
Recommend Dilution	ELISA. Western Blot.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	A 15 residue synthetic peptide derived from specific domain of Human TG2 protein
Specificity	Reacts with Human 77 kDa TGM2 protein. This antibody does not cross reacts with Guinea Pig or any isoformes.
Formulation	Label: Biotin State: Liquid purified antibody
Purification	Affinity Chromatography on Protein A
Conjugation	Biotin
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	transglutaminase 2
Database Link	Entrez Gene 7052 Human UniProt ID P21980
Background	Transglutaminase II catalyzes calcium-dependent post-translational modification of proteins by formation of an isopeptide bond within or between polypeptide chains. It is also known as TGC, tTG, type II-, Gh, cytosolic-, liver-, endothelial-, erythrocyte-, cellular-transglutaminase. Different tissues and cell types express varying amounts of tissue transglutaminase with a markedly hugh expression in rheumatoid lesions. It is implicated in programmed cell death, signal transduction, drug-resistance, cell growth, endocytosis, insulin secretion, cell adhesion, cataract formation, and wound healing.
Synonyms	TGase C, TGase-H, Tissue transglutaminase
Reference Data

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