OLIG2 Rabbit Polyclonal Antibody
CAT#: AP10449SU-N
OLIG2 rabbit polyclonal antibody, Serum
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CNY 6,600.00
货期*
8周
规格
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Specifications
Product Data | |
Applications | ELISA, IHC, WB |
Recommend Dilution | ELISA. |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide derived from C-terminal domain of Human OLIG2 |
Specificity | Reacts with Human 32 kDa protein. |
Formulation | 0.1M Tris 0.1M Glycine, 2% Sucrose State: Serum State: Lyophilized serum Preservative: None |
Reconstitution Method | Restore in distilled water. |
Conjugation | Unconjugated |
Storage Condition | Prior to reconstitution store the antibody at -20°C. |
Gene Name | oligodendrocyte lineage transcription factor 2 |
Database Link | |
Background | Olig2 is a transcription factor which is required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. Expressed in the ventral spinal cord as early as 9.5 dpc and scattered in the mantle zone, likely corresponding to oligodendrocyte progenitors migrating out from their site of origin. From 10.5 through 14.5 dpc, Olig2 is expressed in numerous cells in the ventricular and subventricular zones of the lateral and medial ganglionic eminences, suggesting that expression might not be limited to the oligodendrocytic lineage. Olig2 has further been shown to be critical in the proliferation of malignant glioma in brain tumors (Ligon et al., 2007). |
Synonyms | OLIG2, BHLHB1, PRKCBP2, RACK17, Oligodendrocyte transcription factor 2, Oligo2, bHLHB1 |
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