UBQLN2 (N-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	ELISA: 1/1,000. Western Blot: 1/1000. Immunohistochemistry: 1/50-1/100.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 20~50 amino acids from the N-terminal region of Human Dsk2.
Specificity	This antibody is specific to Ubiquilin-2 (UBQLN2/DSK2) (N-term).
Formulation	PBS with 0.09% (W/V) Sodium Azide as preservative. State: Purified State: Liquid purified Ig fraction.
Concentration	lot specific
Purification	Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	ubiquilin 2
Database Link	Entrez Gene 29978 Human UniProt ID Q9UHD9
Background	Dsk2 increases the half-life of proteins destined to be degraded by the proteasome, and may modulate proteasome-mediated protein degradation. The Dsk2 protein binds UBE3A and BTRC, and interacts with the 19S proteasome subunit. In the cytoplasm, Dsk2 colocalizes with the proteasome; it is also associated with fibers in mitotic cells in the nucleus. Dsk2 is highly expressed in mitotic cells from metaphase to telophase, while expression in non-mitotic cells is very low.
Synonyms	UBQLN1, UBQLN2, PLIC1, PLIC-1, DA41, PLIC2, PLIC-2, N4BP4, Chap1, DSK2 homolog, HRIHFB2157
Note	Predicted Molecular Weight: 65696 Da
Reference Data

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