Seladin 1 (DHCR24) (N-term) Rabbit Polyclonal Antibody

CAT#: AP12497PU-N

Seladin 1 (DHCR24) (N-term) rabbit polyclonal antibody, Purified



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CNY 6,160.00


货期*
5周

规格
    • 400 ul

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Specifications

Product Data
Applications WB
Recommend Dilution ELISA: 1/1,000.
Western Blot: 1/50-1/100.
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human DHCR24.
Specificity This antibody detects DHCR24 (N-term).
Formulation PBS with 0.09% (W/V) Sodium Azide as preservative.
State: Purified
State: Liquid purified Ig fraction.
Concentration lot specific
Purification Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Conjugation Unconjugated
Storage Condition Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Gene Name 24-dehydrocholesterol reductase
Background DHCR24 is a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. This protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of its gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells.
Synonyms 24-dehydrocholesterol reductase, KIAA0018
Note Molecular weight: 60101 Da
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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