MEKK1 (MAP3K1) pThr1383 Rabbit Polyclonal Antibody

Specifications

Product Data
Recommend Dilution	ELISA: 1/1,000. Dot Blot: 1/100-1/500.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T1383 of human MAP3K1.
Specificity	This antibody detects MAP3K1 pThr1383. Predicted to cross react with Mouse (100% Antigen Homology).
Formulation	PBS with 0.09% (W/V) Sodium Azide as preservative. State: Aff - Purified State: Liquid purified Ig fraction.
Concentration	lot specific
Purification	Protein A Affinity Chromatography. Then, the antibody fraction is peptide affinity purified in a 2-step procedure with peptides. The antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	mitogen-activated protein kinase kinase kinase 1
Database Link	Entrez Gene 4214 Human UniProt ID Q13233
Background	Component of a protein kinase signal transduction cascade. Activates the ERK and JNK kinase pathways by phosphorylation of MAP2K1 and MAP2K4. Activates CHUK and IKBKB, the central protein kinases of the NF-kappa-B pathway.
Synonyms	MAPKKK1, MEKK, MEKK1, MAPK/ERK kinase kinase 1
Note	Molecular weight: 164340 Da
Reference Data

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