B Raf (BRAF) pSer445 Rabbit Polyclonal Antibody

CAT#: AP12840PU-N

B Raf (BRAF) pSer445 rabbit polyclonal antibody, Aff - Purified



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CNY 6,314.00


货期*
5周

规格
    • 400 ul

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Specifications

Product Data
Recommend Dilution ELISA: 1/1,000.
Dot Blot: 1/500.
Reactivity Human
Host Rabbit
Clonality Polyclonal
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S445 of human BRAF.
Specificity This antibody detects BRAF pSer445.
Predicted to cross react with Mouse (100% Antigen Homology).
Formulation PBS with 0.09% (W/V) Sodium Azide as preservative.
State: Aff - Purified
State: Liquid purified Ig fraction.
Concentration lot specific
Purification Protein A Affinity Chromatography. Then, the antibody fraction is peptide affinity purified in a 2-step procedure with peptides. The antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Conjugation Unconjugated
Storage Condition Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Gene Name B-Raf proto-oncogene, serine/threonine kinase
Background BRAF is involved in the transduction of mitogenic signals from the cell membrane to the nucleus. It may play a role in the postsynaptic responses of hippocampal neuron. Defects in BRAF are a cause of cardiofaciocutaneous syndrome (CFC syndrome), and a wide range of cancers such as lung cancer, non-Hodgkins lymphoma, and colorectal cancer.
Synonyms BRAF, BRAF1, RAFB1, p94
Note Molecular weight: 84437 Da
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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