CDC25A pSer79 Rabbit Polyclonal Antibody

Specifications

Product Data
Recommend Dilution	ELISA: 1/1,000. Dot Blot: 1/500.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S79 of human Cdc25A.
Specificity	This antibody detects Cdc25A pSer79. Predicted to cross react with Mouse (100% Antigen Homology).
Formulation	PBS with 0.09% (W/V) Sodium Azide as preservative. State: Aff - Purified State: Liquid purified Ig fraction.
Concentration	lot specific
Purification	Protein A Chromatography followed by two-step phosphospecific peptide affinity purification.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	cell division cycle 25A
Database Link	Entrez Gene 993 Human UniProt ID P30304
Background	CDC25A is a member of the CDC25 family of phosphatases.CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division.CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated.
Synonyms	CDC-25A
Note	Molecular weight: 59087 Da
Reference Data

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