GIT1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	ELISA: 1/1,000. Western Blot: 1/50 - 1/100. Immunohistochemistry: 1/:10 - 1/50.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide corresponding to amino acid residues surrounding Y510 of human GIT1.
Specificity	This antibody reacts to GIT1.
Formulation	PBS with 0.09% (W/V) sodium azide State: Aff - Purified State: Liquid purified Ig
Concentration	lot specific
Purification	Affinity chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	GIT ArfGAP 1
Database Link	Entrez Gene 28964 Human UniProt ID Q9Y2X7
Background	GIT1 is a GTPase-activating protein for the ADP ribosylation factor family. It may serve as a scaffold to bring together molecules to form signaling modules controlling vesicle trafficking, adhesion and cytoskeletal organization. It increases the speed of cell migration, as well as the size and rate of formation of protrusions, possibly by targeting PAK1 to adhesions and the leading edge of lamellipodia.
Synonyms	GRK-interacting protein 1, CAT1
Reference Data

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