Integrin Linked Kinase (ILK) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	ELISA: 1/1,000. Immunohistochemistry: 1/10 - 1/50.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide corresponding to amino acid residues surrounding Y343 of human ILK.
Specificity	This antibody reacts to ILK.
Formulation	PBS with 0.09% (W/V) sodium azide State: Aff - Purified State: Liquid purified Ig
Concentration	lot specific
Purification	Affinity chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	integrin linked kinase
Database Link	Entrez Gene 3611 Human UniProt ID Q13418
Background	Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. ILK is a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction.
Synonyms	ILK-1, ILK-2, p59ILK, ILK, ILK1, ILK2
Reference Data

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