CYP21A2 (N-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	ELISA: 1/1000. Western blotting: 1/1000.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 59~87 amino acids from the N-terminal region of Human CYP21A2.
Specificity	This antibody recognizes CYP21A2.
Formulation	PBS with 0.09% (W/V) Sodium Azide as preservative State: Purified State: Liquid purified Ig fraction.
Concentration	lot specific
Purification	Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	55887 Da
Gene Name	cytochrome P450 family 21 subfamily A member 2
Database Link	Entrez Gene 1589 Human UniProt ID P08686
Background	CYP21A2 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates steroids at the 21 position. Its activity is required for the synthesis of steroid hormones including cortisol and aldosterone. Mutations in CYP21A2 gene cause congenital adrenal hyperplasia.
Synonyms	Cytochrome P450 21, CYP21, CYP21B, Cytochrome P450 XXI, Steroid 21-hydroxylase, 21-OHase, Cytochrome P450-C21, Cytochrome P-450c21, Cytochrome P450-C21B
Reference Data

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