PI 3 Kinase catalytic subunit gamma (PIK3CG) (C-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	ELISA: 1/1,000. Western Blot: 1/100-1/500 Immunohistochemistry: 1/50-1/100.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	This PI3KCG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1073~1102 amino acids from the C-terminal region of Human PI3KCG.
Specificity	This antibody reacts to PI3KCG.
Formulation	PBS with 0.09% (W/V) sodium azide State: Purified State: Liquid purified Ig
Concentration	lot specific
Purification	Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
Database Link	Entrez Gene 5294 Human UniProt ID P48736
Background	PI3KCG belongs to the pi3/pi4-kinase family of proteins. This protein is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells.
Synonyms	PI3-kinase subunit gamma, PI3K-gamma, p120-PI3K
Reference Data

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