FMO3 (N-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	Western blot: 1:100 - 1:500. ELISA: 1:1,000.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide selected from the N-terminal region of human FMO3
Specificity	This antibody detects FMO3 at N-term.
Formulation	PBS with 0.09% (W/V) sodium azide State: Liquid Ig fraction
Concentration	lot specific
Purification	Purified through a protein A column, followed by peptide affinity purification
Conjugation	Unconjugated
Storage Condition	Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Gene Name	flavin containing monooxygenase 3
Database Link	Entrez Gene 2328 Human UniProt ID P31513
Background	FMO3 is involved in the oxidative metabolism of a variety of xenobiotics such as drugs and pesticides. It N-oxygenates primary aliphatic alkylamines as well as secondary and tertiary amines. It plays an important role in the metabolism of trimethylamine (TMA), via the production of TMA N-oxide (TMAO). Is also able to perform S-oxidation when acting on sulfide compounds.
Synonyms	FMO form 2, FMO II, Dimethylaniline oxidase 3
Note	Molecular weight: 60033 Da
Reference Data
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Drug metabolism - cytochrome P450

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