LRRC32 Rabbit Polyclonal Antibody
CAT#: AP17415PU-N
LRRC32 rabbit polyclonal antibody, Purified
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CNY 6,160.00
货期*
5周
规格
Cited in 3 publications. |
Specifications
Product Data | |
Applications | IHC, WB |
Recommend Dilution | Western Blot: 1/1000. Immunohistochemistry on Paraffin Sections: 1/10-1/50. |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | KLH conjugated synthetic peptide between 234~260 amino acids from the Center region of Human GARP. |
Specificity | This antibody detects GARP at the center region. Cellular Location: Membrane; Single-pass type I membrane protein. Tissue Location: Preferentially expressed in regulatory T-cells (T(regs)). |
Formulation | PBS State: Purified State: Liquid purified Ig fraction Preservative: 0.09% Sodium Azide |
Concentration | lot specific |
Purification | Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS |
Conjugation | Unconjugated |
Storage Condition | Store undiluted at 2-8°C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. |
Predicted Protein Size | 71979 Da |
Gene Name | leucine rich repeat containing 32 |
Database Link | |
Background | GARP, also known as leucine rich repeat containing 32, is a type I membrane protein with twenty-two leucine-rich repeats and a short intracytoplasmic region. GARP was identified based on the analysis of gene expression profiling of Treg and Th cells following TCR stimulation. |
Synonyms | Garpin, D11S833E |
Reference Data | |
Protein Families | Transmembrane |
Citations (3)
The use of this Antibodies has been cited in the following citations: |
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Platelet-Derived GARP Induces Peripheral Regulatory T Cells-Potential Impact on T Cell Suppression in Patients with Melanoma-Associated Thrombocytosis
,Zimmer, N;Krebs, FK;Zimmer, S;Mitzel-Rink, H;Kumm, EJ;Jurk, K;Grabbe, S;Loquai, C;Tuettenberg, A;,
Cancers
,PubMed ID 33291452
[LRRC32]
|
GARP as an Immune Regulatory Molecule in the Tumor Microenvironment of Glioblastoma Multiforme
,Zimmer, N;Kim, E;Sprang, B;Leukel, P;Khafaji, F;Ringel, F;Sommer, C;Tuettenberg, J;Tuettenberg, A;,
Int J Mol Sci
,PubMed ID 31357555
[LRRC32]
|
A key role of GARP in the immune suppressive tumor microenvironment
,Hahn SA, Neuhoff A, Landsberg J, Schupp J, Eberts D, Leukel P, Bros M, Weilbaecher M, Schuppan D, Grabbe S, Tueting T, Lennerz V, Sommer C, Jonuleit H, Tuettenberg A,
Oncotarget
,PubMed ID 27248166
[LRRC32]
|
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