HFE (Center) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	Western blot: 1:50 - 1:100. ELISA: 1:1,000.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide selected from the Center region of human HFE
Specificity	This antibody detects HFE at Center.
Formulation	PBS with 0.09% (W/V) sodium azide State: Liquid Ig fraction
Concentration	lot specific
Purification	Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
Conjugation	Unconjugated
Storage Condition	Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Gene Name	hemochromatosis
Database Link	Entrez Gene 3077 Human UniProt ID Q30201
Background	HFE is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in its gene.
Synonyms	dJ221C16.10.1; hemochromatosis; HFE1; HH; HLA-H; HLAH; MGC103790; MVCD7
Note	Molecular weight: 40108 Da
Reference Data
Protein Families	Druggable Genome, Transmembrane

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