RRM2 (Center) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide selected from the Center region of human RRM2
Specificity	This antibody reacts to RRM2.
Formulation	PBS with 0.09% (W/V) sodium azide State: Liquid purified Ig
Concentration	lot specific
Purification	Saturated Ammonium Sulfate (SAS) precipitation
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	ribonucleotide reductase regulatory subunit M2
Database Link	Entrez Gene 6241 Human UniProt ID P31350
Background	RRM2 is one of two non-identical subunits for ribonucleotide reductase. This reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides. Synthesis of the protein (M2) is regulated in a cell-cycle dependent fashion.
Synonyms	Ribonucleotide reductase small subunit, Ribonucleotide reductase small chain
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Glutathione metabolism, Metabolic pathways, p53 signaling pathway, Purine metabolism, Pyrimidine metabolism

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