AF10 (MLLT10) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	Western blot: 1/500-1/1000. Immunohistochemistry on Paraffin Sections: 1/50-1/200. Immunofluorescence: 1/50-1/200.
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to amino acids 200-250 of Human AF-10.
Specificity	This antibody detects endogenous levels of AF-10 protein. (region surrounding Glu237)
Formulation	Phosphate buffered saline (PBS), pH~7.2 State: Aff - Purified State: Liquid purified Ig fraction (> 95% by SDS-PAGE) Preservative: 0.05% Sodium Azide
Concentration	1.0 mg/ml
Purification	Immunoaffinity Chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	~ 109 kDa
Gene Name	myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10
Database Link	Entrez Gene 17354 MouseEntrez Gene 361285 RatEntrez Gene 8028 Human UniProt ID P55197
Background	AF10 is a putative transcription factor containing a leucine zipper motif. A t (10;11) (p12;q23) chromosomal translocation present in a proportion of acute myeloid leukaemias results in expression of an AF10 (carboxy terminus) MLL (amino terminus) fusion protein.
Synonyms	AF10; DKFZp686E10210; MGC75086
Reference Data
Protein Families	Druggable Genome, Transcription Factors

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