TRIM38 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	Western Blot: 1/500 - 1/1000.
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Specificity	This antibody detects endogenous levels of RNF15 protein. (region surrounding Glu193)
Formulation	Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. State: Aff - Purified State: Liquid purified Ig fraction > 95% (by SDS-PAGE)
Concentration	1.0 mg/ml
Purification	Affinity-chromatography using epitope-specific immunogen
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	~ 58 kDa
Gene Name	tripartite motif containing 38
Database Link	Entrez Gene 214158 MouseEntrez Gene 10475 Human UniProt ID O00635
Background	The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. RNF152 (RINGfinger protein 152) is a 203 amino acid protein that contains one RING-type zinc finger and may be involved in protein degradation events throughout the cell. The gene encoding RNF152 maps to human chromosome 18, which houses over 300 protein-coding genes and contains nearly 76 million bases. There are a variety of diseases associated with defects in chromosome 18- localized genes, some of which include Trisomy 18 (also known as Edwards syndrome), Niemann-Pick disease, hereditary hemorrhagic telangiectasi,a erythropoietic protoporphyria and follicular lymphomas.
Synonyms	RORET, RING finger protein 15
Reference Data
Protein Families	Druggable Genome

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