67kDa Laminin Receptor (RPSA) Rabbit Polyclonal Antibody

CAT#: AP20782PU-N

67kDa Laminin Receptor (RPSA) rabbit polyclonal antibody, Aff - Purified



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CNY 1,999.00

CNY 4,640.00


货期*
2周

规格
    • 100 ug

Product images

Specifications

Product Data
Applications IHC, WB
Recommend Dilution Western blot: 1/500 - 1/1000.
Immunohistochemistry on paraffin sections: 1/50 - 1/200.
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Specificity This antibody detects endogenous levels of Laminin-R protein.
(region surrounding Gln215)
Formulation Phosphate buffered saline (PBS), pH 7.2.
State: Aff - Purified
State: Liquid purified Ig fraction
Preservative: 0.05% sodium azide
Concentration 1.0 mg/ml
Purification Affinity chromatography (> 95% (by SDS-PAGE)
Conjugation Unconjugated
Storage Condition Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Predicted Protein Size ~ 40 kDa
Gene Name ribosomal protein SA
Background Laminin receptor (Laminin-R) has a heterodimeric structure similar to that of receptors for other extracellular matrix proteins such as Fibronectin and Vitronectin. Incorporation of Laminin-R into lysosomal membranes makes it possible for lysosomes to attach to surfaces coated with Laminin. This and other properties identify Laminin-R as a member of the integrin family of cell adhesion receptors. The Laminin-R precursor is a polypeptide whose expression is consistently upregulated in aggressive carcinoma. The precursor, which is also identified as p40 ribosome-associated protein, appears to be a multifunctional protein involved in the translational machinery. Laminin-R (also known as colon carcinoma Laminin-binding protein) is found at nine-fold higher levels in colon carcinoma than in adjacent normal colonic epithelium. Addi-tionally, the level of the Laminin-R is higher in the lung cancer cell line than in the lung cell line.
Synonyms 40S ribosomal protein SA, LAMBR, LAMR1, LamR, Laminin receptor 1, 37LRP, LRP/LR, 67LR, NEM/1CHD4
Reference Data
Protein Families Druggable Genome
Protein Pathways Ribosome
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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