Cytochrome P450 Reductase (POR) Goat Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, WB
Recommend Dilution	Peptide ELISA: Detection limit: 1/16000. Western blot: 0.1-0.3 µg/ml. Approx 90kDa band observed in Human, Mouse and Rat Liver lysates (calculated MW of 77.0kDa according to NP_000932.3).
Reactivity	Bovine, Canine, Human, Mouse, Porcine, Rabbit, Rat
Host	Goat
Clonality	Polyclonal
Immunogen	Peptide with sequence from the internal region of the protein sequence according to NP_000932.3.
Specificity	Recognizes Cytochrome P450 Reductase (CYPOR).
Formulation	Tris saline, pH 7.3 containing 0.02% Sodium Azide as preservative and 0.5% BSA as stabilizer. State: Aff - Purified State: Liquid purified Ig fraction.
Concentration	lot specific
Purification	Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	cytochrome p450 oxidoreductase
Database Link	Entrez Gene 5447 Human UniProt ID P16435
Background	P450R is an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in its gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.
Synonyms	CPR, P450R, POR, CYPOR
Reference Data

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