ALDH6A1 (262-272) Goat Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, WB
Recommend Dilution	Peptide ELISA: Limit Dlution: 1/32000. Western blot: 0.1-0.3 µg/ml. Approx 55kDa band observed in Human, Mouse and Rat Kidney lysates.  Immunohistochemistry on Paraffin Sections: 5 µg/ml in Paraffin embedded Human Liver.
Reactivity	Bovine, Canine, Human, Mouse, Porcine, Rat
Host	Goat
Clonality	Polyclonal
Immunogen	Peptide with sequence from the internal region of the protein sequence according to NP_005580.1.
Specificity	Recognizes ALDH6A1 (262-272).
Formulation	Tris saline, pH~7.3 with 0.02% Sodium Azide and 0.5% BSA State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	aldehyde dehydrogenase 6 family member A1
Database Link	Entrez Gene 4329 Human UniProt ID Q02252
Background	ALDH6A1 belongs to the aldehyde dehydrogenases family of proteins. This enzyme plays a role in the valine and pyrimidine catabolic pathways. This protein is a mitochondrial methylmalonate semialdehyde dehydrogenase, and catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids.
Synonyms	MGC40271; MMSADHA; MMSDH
Note	Calculated Molecular Weight: 57.8kDa (NP_005580.1).
Reference Data

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