FANCG (609-622) Goat Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC, WB
Recommend Dilution	ELISA: 1/32000. Immunohistochemistry on Paraffin Sections: 3 µg/ml. Western Blot: 0.5 - 1 µg/ml.
Reactivity	Human, Monkey
Host	Goat
Clonality	Polyclonal
Immunogen	Synthetic peptide from C-term of human FANCG
Specificity	This antibody detects XRCC9 / FANCG (C-term).
Formulation	Tris saline buffer, pH 7.3, 0.5% BSA, 0.02% sodium azide State: Aff - Purified State: Liquid Ig fraction
Concentration	lot specific
Purification	Immunoaffinity chromatography
Conjugation	Unconjugated
Storage Condition	Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Gene Name	Fanconi anemia complementation group G
Database Link	Entrez Gene 2189 Human UniProt ID O15287
Background	FANCG, involved in Fanconi anemia, confers resistance to both hygromycin and mitomycin C. FANCG contains a 5-prime GC-rich untranslated region characteristic of housekeeping genes. The putative 622-amino acid protein has a leucine-zipper motif at its N-terminus. Fanconi anemia is an autosomal recessive disorder with diverse clinical symptoms, including developmental anomalies, bone marrow failure, and early occurrence of malignancies. A minimum of 8 FA genes have been identified. The FANCG gene is responsible for complementation group G.
Synonyms	FACG, Fanconi anemia group G protein
Reference Data
Protein Families	Druggable Genome

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