KMT2B (2703-2715) Goat Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC
Recommend Dilution	ELISA: 1/128000. Immunohistochemistry on Paraffin Sections: 5 µg/ml.
Reactivity	Human, Mouse, Rat, Bovine, Monkey, Porcine, Zebrafish
Host	Goat
Clonality	Polyclonal
Immunogen	Synthetic peptide from C-term of human MLL4
Specificity	This antibody detects MLL4 (C-term).
Formulation	Tris saline buffer, pH 7.3 containing 0.5% BSA as stabilizer and 0.02% sodium azide as preservative State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Immunoaffinity chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	lysine methyltransferase 2B
Database Link	Entrez Gene 75410 MouseEntrez Gene 102550344 RatEntrez Gene 9757 Human UniProt ID Q9UMN6
Background	This gene encodes a protein which contains multiple domains including a CXXC zinc finger, three PHD zinc fingers, two FY-rich domains, and a SET (suppressor of variegation, enhancer of zeste, and trithorax) domain. The SET domain is a conserved C-terminal domain that characterizes proteins of the MLL (mixed-lineage leukemia) family. This gene is ubiquitously expressed in adult tissues. It is also amplified in solid tumor cell lines, and may be involved in human cancer. Two alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene, however, the full length nature of the shorter transcript is not known.
Synonyms	WBP7, HRX2, KIAA0304, KMT2D, MLL2, TRX2
Reference Data
Protein Families	Druggable Genome

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