CD19 (393-421) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	Immunohistochemistry on Paraffin Sections: 5 µg/ml. Western Blot: 1/1000.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	CD19 antibody was raised against kLH-conjugated synthetic peptide between amino acids 393-421 from C-terminal region of human CD19.
Specificity	This antibody reacts to CD19 Antigen (CD19) at aa 393-421.
Formulation	PBS containing 0.09% sodium azide State: Aff - Purified State: Liquid purified Ig fraction
Purification	Immunoaffinity purified
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	CD19 molecule
Database Link	Entrez Gene 930 Human UniProt ID P15391
Background	Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. This gene encodes a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation.
Synonyms	Leu-12, B-cell marker
Reference Data
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	B cell receptor signaling pathway, Hematopoietic cell lineage, Primary immunodeficiency

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