PPAR delta (PPARD) (430-441) Goat Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC, WB
Recommend Dilution	ELISA: 1/16000. Immunohistochemistry on Paraffin Sections: 3.75 µg/ml. Western Blot: 0.3 - 1 µg/ml.
Reactivity	Human, Bovine, Bat, Canine, Chicken, Equine, Hamster, Monkey, Mouse, Porcine, Rabbit, Rat, Zebrafish
Host	Goat
Clonality	Polyclonal
Immunogen	Synthetic peptide from the C-terminus of human PPARD
Specificity	This antibody detects PPAR-delta (C-term). It is expected to recognise isoform 1 (NP_006229) of PPAR delta, but not isoform 2, a shorter protein (NP_803184) with a different C-terminus.
Formulation	Tris saline buffer, pH 7.3 containing 0.5% BSA as stabilizer and 0.02% sodium azide as preservative State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Immunoaffinity chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	peroxisome proliferator activated receptor delta
Database Link	Entrez Gene 19015 MouseEntrez Gene 25682 RatEntrez Gene 5467 Human UniProt ID Q03181
Background	Peroxisome proliferator-activated receptor beta/delta (PPAR beta/delta), a NR1 Thyroid Hormone-Like Receptor, is involved in the regulation of acyl-CoA synthetase 2 expression, lipid metabolism, embryo development, implantation, decidualization, and bone formation. PPAR beta/delta has been identified as a negative target of the APC gene and has been linked to colon cancer.
Synonyms	PPAR-beta, Nuclear hormone receptor 1, NUCI, PPARD, NR1C2, PPARB
Reference Data
Protein Families	Druggable Genome, Nuclear Hormone Receptor, Transcription Factors
Protein Pathways	Acute myeloid leukemia, Pathways in cancer, PPAR signaling pathway, Wnt signaling pathway

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