FMRP (FMR1) (594-607) Goat Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC, WB
Recommend Dilution	ELISA: 1/128000. Immunohistochemistry on Paraffin Sections: 2.5 µg/ml. Western Blot: 0.1 - 0.3 µg/ml.
Reactivity	Human, Bat, Hamster, Monkey, Mouse, Porcine, Rabbit, Rat
Host	Goat
Clonality	Polyclonal
Immunogen	Synthetic peptide from the internal region (near the C Terminus) of the protein sequence according to NP_002015.1
Specificity	This antibody detects FMR1 / FMRP (C-term).
Formulation	Tris saline, pH 7.3 containing 0.02% sodium azide as preservative and 0.5% BSA as stabilizer State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Immunoaffinity Chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	fragile X mental retardation 1
Database Link	Entrez Gene 14265 MouseEntrez Gene 24948 RatEntrez Gene 700138 MonkeyEntrez Gene 2332 Human UniProt ID Q06787
Background	Translation repressor. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates translation repression (By similarity). RNA-binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs. Associated with polysomes. May play a role in the transport of mRNA from the nucleus to the cytoplasm.
Synonyms	Fragile X mental retardation 1 protein, Protein FMR-1
Reference Data
Protein Families	Druggable Genome

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